Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SB-399885 hydrochloride is an antagonist of 5-HT6 receptor.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
2 mg | ¥ 489 | 5日内发货 | ||
25 mg | ¥ 4,310 | 6-8周 | ||
50 mg | ¥ 5,610 | 6-8周 | ||
100 mg | ¥ 10,300 | 6-8周 |
SB-399885 hydrochloride 的其他形式现货产品:
产品描述 | SB-399885 hydrochloride is an antagonist of 5-HT6 receptor. |
体内活性 | SB-399885 hydrochloride 10 mg/kg significantly increases wakefulness (W) (F(3,15)=3.32, P<0.05) while slow wave sleep (SWS), rapid-eye-movement sleep (REMS) and the number of REM periods are reduced (F(3,15)=4.0, P<0.01; F(3,15)=3.14, P<0.05 and F(3,15)=2.62, P<0.05, respectively) Compare with the control vehicle . Analysis of sleep variables in 2-h blocks shows that SB-399885 hydrochloride 10 mg/kg increases W (F(3,15)=5.48, P<0.01) and reduces SWS (F(3,15)=5.42, P<0.01) and REMS (F(3,15)= 4.05, P<0.01) during the first 2-h period. SB-399885 hydrochloride 5 and 10 mg/kg augment light sleep over the first (F(3,15)=3.46,P<0.01 and F(3,15)= 3.65, P<0.01, respectively) and the second (F(3,15)=3.23, P<0.05 and F(3,15)=3.08, P<0.05, respectively) 2-h recording periods. SB-399885 hydrochloride 10 mg/kg significantly increases REMS latency (F(3,15)=3.60, P<0.01) and reduces the number of REM periods during the first 2-h of recording (F(3,15)=3.88, P<0.01). |
分子量 | 482.81 |
分子式 | C18H22Cl3N3O4S |
CAS No. | 402713-81-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 125 mg/mL (258.90 mM), Sonication and heating are recommended.
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.0712 mL | 10.356 mL | 20.7121 mL | 51.7802 mL |
5 mM | 0.4142 mL | 2.0712 mL | 4.1424 mL | 10.356 mL | |
10 mM | 0.2071 mL | 1.0356 mL | 2.0712 mL | 5.178 mL | |
20 mM | 0.1036 mL | 0.5178 mL | 1.0356 mL | 2.589 mL | |
50 mM | 0.0414 mL | 0.2071 mL | 0.4142 mL | 1.0356 mL | |
100 mM | 0.0207 mL | 0.1036 mL | 0.2071 mL | 0.5178 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
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